Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)
Agency
National Institutes of Health
Assistance Listings
- 859 -- Biomedical Research and Research Training
- 840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
- 361 -- Nursing Research
- 173 -- Research Related to Deafness and Communication Disorders
- 213 -- Research and Training in Complementary and Integrative Health
- 866 -- Aging Research
- 279 -- Drug Use and Addiction Research Programs
- 172 -- Human Genome Research
- 233 -- National Center on Sleep Disorders Research
- 838 -- Lung Diseases Research
- 865 -- Child Health and Human Development Extramural Research
- 839 -- Blood Diseases and Resources Research
- 113 -- Environmental Health
- 350 -- National Center for Advancing Translational Sciences
- 837 -- Cardiovascular Diseases Research
- 867 -- Vision Research
- 121 -- Oral Diseases and Disorders Research
- 273 -- Alcohol Research Programs
- 846 -- Arthritis, Musculoskeletal and Skin Diseases Research
- 879 -- Medical Library Assistance
Last Updated
May 27, 2026
Description
The National Institutes of Health (NIH), including the participating Institutes, Centers and Offices, intends to publish a Notice of Funding Opportunity (NOFO) to invite eligible United States small business concerns (SBCs) to submit Small Business Technology Transfer (STTR) Phase I, and Fast-Track grant applications for the Small Business Transition Grant. Through this NOFO, NIH will support early-career scientists transitioning to entrepreneurship. In addition to funding research and development efforts at the SBC, a major component of this NOFO is entrepreneurial training, mentoring, and career development of the PD/PI.
Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop responsive projects, including identification of complementary industry mentors and career development resources. This NOFO will utilize the R41/R42 activity code. United States small businesses that have the research capabilities and technological expertise to contribute to the R&D mission(s) of the NIH awarding components identified in this NOFO are encouraged to begin to consider applying for this new NOFO. This opportunity is available to first-time Principal Investigators, and key personnel must include a mentor with measurable effort committed to the project.
Eligibility
Eligible applicants
- Small businesses
Additional information
Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity. Individuals are eligible to serve as the PD/PI if they have never been an independent PD/PI on an NIH or CDC research, or corresponding non-NIH peer-reviewed research grant, and are a U.S. Citizen or Lawful Permanent Resident.
Grantor contact information
NIH SEED (Small business Education and Entrepreneurial Development) Office of Extramural Research (OER) 301-827-8595 Email: SEEDinfo@nih.gov
Documents
No documents are currently available.
Link to additional information
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Forecasted
- Estimated Post Date: November 5, 2026
- Estimated Application Due Date: January 5, 2027
- Estimated Due Date Description: Not available
- Estimated Award Date: June 1, 2027
- Estimated Project Start Date: July 1, 2027
- Fiscal Year: 2027
Application process
This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates. View on Grants.gov
Award
- Program Funding: $--
- Expected awards: --
- Award Minimum: $--
- Award Maximum: $--
Funding opportunity number
PAR-27-040
Cost sharing or matching requirement
No
Funding instrument type
Grant
Opportunity Category
Discretionary
Opportunity Category Explanation
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Category of Funding Activity
Health
Category Explanation
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History
- Version: 1
- Forecast posted date: May 27, 2026
- Archive date: --